Matrix Binding Regulates SATB 1 - mediated Transcriptional Repression
نویسندگان
چکیده
The abbreviations used are: MMTV, mouse mammary tumor virus; LTR, long terminal repeat; SATB1, special AT-rich binding protein 1; CDP, CCAAT-displacement protein; NRE, negative regulatory element; NURD, nucleosome remodeling and deacetylase complex; CHRAC, chromatin-accessibility complex; ACF, ATP-utilizing chromatin assembly and remodeling factor; YY1, ying-yang 1; GFP, green fluorescent protein; GR, glucocorticoid receptor; DMEM, Dulbecco’s modified Eagle’s medium; NMTS, nuclear matrix targeting sequence; DAPI, 4’,6-diamidino-2-phenylindole; PMSF, phenylmethylsulfonyl fluoride; MAR, nuclear matrix-associated region; NLS, nuclear localization signal; DEX, dexamethasone; ID, internal deletion; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; RPA, ribonuclease protection assay; FACS, fluorescence-activated cell sorter; HAT, histone acetyltransferase; HDAC, histone deacetylase; HRE, hormone responsive element; EMSA, electrophoretic mobility shift assay; PBS, phosphate-buffered saline; IRES, internal ribosomal entry site; DBD, DNA-binding domain; IL-2Rα, interleukin-2 receptor alpha; siRNA, small interfering RNA.
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